Nise D Spray 35gm

INTRODUCTION ABOUT NISE D SPRAY

NISE D SPRAY is a combination of Diclofenac, Linseed Oil, Menthol and Methyl Salicylate which belongs to the group of medicines called Analgesics, Flaxseed oil, Cooling agents and Organic esters. It is indicated to provide relief from acute musculoskeletal disorders such as sprains, strains, tendonitis, shoulder pain, bursitis, hand, neck, sciatica, muscle stiffness, joint pain, backache and pain of osteoarthritis of joints which is manageable by topical medicines.

NISE D SPRAY is not recommended for use in patients who have advanced kidney disease, had asthma, urticaria (allergic reaction) after use of NSAIDs such as aspirin, setting of coronary artery bypass graft surgery, broken or irritated skin.

NISE D SPRAY should not be used in pregnant women especially in the late pregnancy and it should be used with caution in breast-feeding women. It should not be used in children below 2 years of age and children having flu, chickenpox or fever.

Caution must be exercised while using NISE D SPRAY in elderly patients. The most common side effects of using NISE D SPRAY are skin rash, oedema, wheals, papules (tender bump), scaly skin, reddening of the skin, itching or prickling sensation may occur at the site of application. Ask for your doctor’s advise if any of these doesn’t improve or worsens.

USES OF NISE D SPRAY

Manages pain, swelling and inflammation associated with:

• Sprains, strains, tendonitis, shoulder pain, bursitis, hand, neck, sciatica, muscle stiffness, joint pain and backache

HOW NISE D SPRAY WORKS

NISE D SPRAY helps in relieving aches and pain, where diclofenac is a non-steroidal anti-inflammatory drug which causes relief in pain and inflammation by inhibiting the factors that cause inflammation and pain called prostaglandins. Linseed oil helps in minimizing the skin irritation and soothes and calms the skin. Methyl salicylate is an organic ester, which is derived from plants acts by dilating the blood vessels and increasing the blood flow. It causes irritation of the skin and as a result of counter irritation, there is a sensation of warmth and relief in musculoskeletal pain. Menthol acts by imparting coolness to the skin and then warmth.

DIRECTIONS FOR USE

Apply NISE D SPRAY as advised by your physician. It is for topical use only. Wash your hands before and after use. Gently rub NISE D SPRAY on the affected area till it disappears. Do not cover the applied areas with a bandage and do not apply on cuts and open wounds. Bathing should be avoided for at least 1 hour after the application of NISE D SPRAY. Avoid the contact of this medicine in your eyes, ears or nose and mouth.

Your doctor will decide the duration and frequency of the management depending upon your age and disease condition.

SIDE EFFECTS OF NISE D SPRAY

HOW TO MANAGE SIDE EFFECTS

Skin Rash Or Itching

Avoid hot showers because hot water can irritate your skin further. Do not scratch the affected area. Avoid sun exposure or UV rays as it may sensitize your skin. Use sunscreen and protective clothing when going outdoor. Regularly moisturize your skin after consulting the doctor. Consult your doctor if the symptom does not improve.

WARNING & PRECAUTIONS

PREGNANCY

CONTRAINDICATED

NISE D SPRAY should not be used in pregnant women especially in the late pregnancy. Consult your doctor before using it.

BREASTFEEDING

MONITORING REQUIRED

NISE D SPRAY should be used with caution in breastfeeding women only if considered clearly necessary. Consult your doctor before using it.

DRIVING AND USING MACHINES

USE WITH CAUTION

Effects of NISE D SPRAY on driving and using machines is not known. Consult with your doctor.

ALCOHOL

CONSULT YOUR DOCTOR

Avoid consumption of alcohol while using NISE D SPRAY.

KIDNEY

CONSULT YOUR DOCTOR

NISE D SPRAY is not recommended for use in patients having advanced renal disease. It should be used with caution in patients with impaired kidney function. Consult your doctor before using it.

LIVER

USE WITH CAUTION

NISE D SPRAY should be used with caution in patients having liver diseases. Consult your doctor before using it.

ALLERGY

CONTRAINDICATED

Do not use NISE D SPRAY if you are allergic to Diclofenac, Linseed Oil, Menthol, Methyl Salicylate or other NSAIDs (such as aspirin).

LUNGS

CONTRAINDICATED

NISE D SPRAY is not recommended for use in patients who had an asthmatic attack after the use of NSAIDs such as aspirin or indomethacin. Consult your doctor before using it.

HEART DISEASE

CONTRAINDICATED

NISE D SPRAY is not recommended for use in patients in the setting of coronary artery bypass graft surgery. Consult your doctor before using it.

INTERACTIONS

A. Drug–Drug Interactions:

Before using NISE D SPRAY, inform your doctor if you are taking any of the following medicines:

• NSAIDs such as aspirin, ibuprofen (used to manage pain and inflammation), cyclo-oxygenase-2 (COX2) inhibitors such as celecoxib, valdecoxib (used to manage osteoarthritis or rheumatoid arthritis)
• Diuretics such as spironolactone, furosemide (used to manage excess fluid in the body)
• Cyclosporine, tacrolimus (used to supress immune system such as after transplants)
• Lithium, selective serotonin-re-uptake inhibitors (SSRIs) such as citalopram, sertraline (used to manage anxiety and depression)
• Digoxin, amiodarone (medicine used in managing an irregular heartbeat or heart failure), antihypertensives such as ramipril, azilsartan (used to lower down the blood pressure)
• Warfarin (used as a blood-thinning agents that reduce blood clotting)
• Oral hypoglycaemics such as metformin, sitagliptin (used to control blood sugar)
• Corticosteroids such as prednisolone (used as anti-inflammatory medicines)
• Antacids such as magnesium sulphate (used to manage heartburn, indigestion)
• Chloramphenicol, quinolone antibiotics such as ciprofloxacin, moxifloxacin (used to manage some infections)
• Ketoconazole, fluconazole, miconazole, voriconazole (used to manage fungal infections)
• Sulfinpyrazone (used to manage gout)
• Mifepristone (used to terminate pregnancy)
• Metoclopramide, domperidone (medicines used to control nausea)
• Cholestyramine (used to manage high cholesterol or high blood fats)
• Imatinib, methotrexate (used to manage certain cancers)
• Sunscreens, cosmetics, lotions, moisturizers, insect repellents

Overdosage:

In case of accidental ingestion or too much application of NISE D SPRAY, consult your doctor immediately or visit the nearby hospital.