If you are allergic to Mexiletine, any local anaesthetics or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before taking MEXILETINE. MEXILETINE is not recommended for children and adolescents below 18 years of age. Avoid intake of alcohol with MEXILETINE as it may worsen dizziness or drowsiness. MEXILETINE may cause dizziness, drowsiness or blurred vision in some people. Therefore, drive only if you are alert after taking MEXILETINE. Inform your doctor if you have a genetic problem with an enzyme in your body called CYP2D6 which breaks down (metabolizes) certain medicines in your body too slowly, because a different dose may be applicable to you. If you start to smoke or quit smoking while taking MEXILETINE, inform your doctor as smoking impacts the Mexiletine blood levels, and your dose may need to be adjusted accordingly.

Drug-Drug Interaction: Inform your doctor if you are taking medicines used to treat heart problems (amiodarone, verapamil, propranolol), anticonvulsants (phenytoin), antidepressants (fluvoxamine), a medicine used to treat stomach ulcer and gastric acid reflux (omeprazole), opioid analgesics (morphine), antacids, anticholinergic agent (atropine), anti-asthma drug (theophylline), a medicine used to prevent and treat nausea and vomiting (metoclopramide), caffeine-containing medications, antibiotics (ciprofloxacin, rifampicin), antidiabetic drug (metformin), blood thinner medicines (warfarin), or muscle relaxant (tizanidine).

Drug-Food Interaction: You are recommended to reduce caffeine intake by half while taking MEXILETINE as it can increase caffeine levels in the blood. Also, limit or avoid alcohol intake while taking MEXILETINE as it may worsen dizziness and drowsiness.

Drug-Disease Interaction: Avoid taking MEXILETINE if you have sinus syndrome (a type of heart rhythm disorder), long QT syndrome (an inherited heart condition), or heart problems which can cause ankle swelling or shortness of breath or some types of heart rhythm disorders. If you have low or high electrolyte blood levels, abnormal blood counts, seizures (fits), kidney, liver, or heart problems, please inform your doctor before taking MEXILETINE.

• Maintain a low-salt diet and minimize eating processed foods as they contain more sodium. Try to replace salt with spices or herbs to add flavour to the food.

• Do regular exercise as it helps lower blood pressure and keeps blood vessels and the heart in good condition.

• Quit smoking as smoking increases blood pressure and heart rate.

• Eat a balanced and healthy diet that includes plenty of vegetables, fruits, and low-fat or fat-free products.